DNA-barcoded signal amplification for imaging mass cytometry enables sensitive and highly multiplexed tissue imaging

Imaging mass cytometry (IMC) is a highly multiplexed, antibody-based imaging method that captures heterogeneous spatial protein expression patterns at subcellular resolution. Here we report the extension of IMC to low-abundance markers through incorporation of the DNA-based signal amplification by e...

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Detalles Bibliográficos
Autores principales: Hosogane, Tsuyoshi, Casanova, Ruben, Bodenmiller, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482679/
https://www.ncbi.nlm.nih.gov/pubmed/37653118
http://dx.doi.org/10.1038/s41592-023-01976-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482679/
https://www.ncbi.nlm.nih.gov/pubmed/37653118
http://dx.doi.org/10.1038/s41592-023-01976-y

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