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Natamycin interferes with ergosterol-dependent lipid phases in model membranes

Natamycin is an antifungal polyene macrolide that is used as a food preservative but also to treat fungal keratitis and other yeast infections. In contrast to other polyene antimycotics, natamycin does not form ion pores in the plasma membrane, but its mode of action is poorly understood. Using nucl...

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Detalles Bibliográficos
Autores principales: Akkerman, Vibeke, Scheidt, Holger A., Reinholdt, Peter, Bashawat, Mohammad, Szomek, Maria, Lehmann, Max, Wessig, Pablo, Covey, Douglas F., Kongsted, Jacob, Müller, Peter, Wüstner, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482743/
https://www.ncbi.nlm.nih.gov/pubmed/37691996
http://dx.doi.org/10.1016/j.bbadva.2023.100102