Assessment of the roles of Spt5-nucleic acid contacts in promoter proximal pausing of RNA polymerase II

Promoter proximal pausing of RNA polymerase II (Pol II) is a critical transcriptional regulatory mechanism in metazoans that requires the transcription factor DRB sensitivity-inducing factor (DSIF) and the inhibitory negative elongation factor (NELF). DSIF, composed of Spt4 and Spt5, establishes the...

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Detalles Bibliográficos
Autores principales: Dollinger, Roberta, Deng, Eilene B., Schultz, Josie, Wu, Sharon, Deorio, Haley R., Gilmour, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482750/
https://www.ncbi.nlm.nih.gov/pubmed/37517697
http://dx.doi.org/10.1016/j.jbc.2023.105106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482750/
https://www.ncbi.nlm.nih.gov/pubmed/37517697
http://dx.doi.org/10.1016/j.jbc.2023.105106

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