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Flanking regions, amyloid cores, and polymorphism: the potential interplay underlying structural diversity

The β-sheet–rich amyloid core is the defining feature of protein aggregates associated with neurodegenerative disorders. Recent investigations have revealed that there exist multiple examples of the same protein, with the same sequence, forming a variety of amyloid cores with distinct structural cha...

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Detalles Bibliográficos
Autores principales: Bhopatkar, Anukool A., Kayed, Rakez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482755/
https://www.ncbi.nlm.nih.gov/pubmed/37536631
http://dx.doi.org/10.1016/j.jbc.2023.105122