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A cytotoxic T cell inspired oncolytic nanosystem promotes lytic cell death by lipid peroxidation and elicits antitumor immune responses

Lytic cell death triggers an antitumour immune response. However, cancer cells evade lytic cell death by several mechanisms. Moreover, a prolonged and uncontrolled immune response conversely leads to T-cell exhaustion. Therefore, an oncolytic system capable of eliciting an immune response by killing...

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Detalles Bibliográficos
Autores principales: Zuo, Zhigui, Yin, Hao, Zhang, Yu, Xie, Congying, Wang, Qinyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482857/
https://www.ncbi.nlm.nih.gov/pubmed/37673934
http://dx.doi.org/10.1038/s41467-023-41335-1