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Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder

Major depressive disorder (MDD) is known to cause significant disability. Genome-wide DNA methylation (DNAm) profiles can be used to estimate biological aging and as epigenetic clocks. However, information on epigenetic clocks reported in MDD patients is inconsistent. Since antidepressants are likel...

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Detalles Bibliográficos
Autores principales: Shindo, Ryota, Tanifuji, Takaki, Okazaki, Satoshi, Otsuka, Ikuo, Shirai, Toshiyuki, Mouri, Kentaro, Horai, Tadasu, Hishimoto, Akitoyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482893/
https://www.ncbi.nlm.nih.gov/pubmed/37673891
http://dx.doi.org/10.1038/s41514-023-00117-1