Novel quinazoline-1,2,3-triazole hybrids with anticancer and MET kinase targeting properties

Oncogenic activation of receptor tyrosine kinases (RTKs) such as MET is associated with cancer initiation and progression. We designed and synthesized a new series of quinazoline derivatives bearing 1,2,3-triazole moiety as targeted anticancer agents. The MET inhibitory effect of synthesized compoun...

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Detalles Bibliográficos
Autores principales: Mortazavi, Motahareh, Eskandari, Masoomeh, Moosavi, Fatemeh, Damghani, Tahereh, Khoshneviszadeh, Mehdi, Pirhadi, Somayeh, Saso, Luciano, Edraki, Najmeh, Firuzi, Omidreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482942/
https://www.ncbi.nlm.nih.gov/pubmed/37673888
http://dx.doi.org/10.1038/s41598-023-41283-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482942/
https://www.ncbi.nlm.nih.gov/pubmed/37673888
http://dx.doi.org/10.1038/s41598-023-41283-2

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