NAD(H) homeostasis underlies host protection mediated by glycolytic myeloid cells in tuberculosis

Mycobacterium tuberculosis (Mtb) disrupts glycolytic flux in infected myeloid cells through an unclear mechanism. Flux through the glycolytic pathway in myeloid cells is inextricably linked to the availability of NAD(+), which is maintained by NAD(+) salvage and lactate metabolism. Using lung tissue...

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Detalles Bibliográficos
Autores principales: Pacl, Hayden T., Chinta, Krishna C., Reddy, Vineel P., Nadeem, Sajid, Sevalkar, Ritesh R., Nargan, Kievershen, Lumamba, Kapongo, Naidoo, Threnesan, Glasgow, Joel N., Agarwal, Anupam, Steyn, Adrie J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482943/
https://www.ncbi.nlm.nih.gov/pubmed/37673914
http://dx.doi.org/10.1038/s41467-023-40545-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482943/
https://www.ncbi.nlm.nih.gov/pubmed/37673914
http://dx.doi.org/10.1038/s41467-023-40545-x

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