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Evolutionary selection of proteins with two folds

Although most globular proteins fold into a single stable structure, an increasing number have been shown to remodel their secondary and tertiary structures in response to cellular stimuli. State-of-the-art algorithms predict that these fold-switching proteins adopt only one stable structure, missin...

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Detalles Bibliográficos
Autores principales: Schafer, Joseph W., Porter, Lauren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482954/
https://www.ncbi.nlm.nih.gov/pubmed/37673981
http://dx.doi.org/10.1038/s41467-023-41237-2