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Evolutionary selection of proteins with two folds
Although most globular proteins fold into a single stable structure, an increasing number have been shown to remodel their secondary and tertiary structures in response to cellular stimuli. State-of-the-art algorithms predict that these fold-switching proteins adopt only one stable structure, missin...
Autores principales: | Schafer, Joseph W., Porter, Lauren L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482954/ https://www.ncbi.nlm.nih.gov/pubmed/37673981 http://dx.doi.org/10.1038/s41467-023-41237-2 |
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