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Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus

Aquaporins are water channels found in the cell membrane, where they allow the passage of water molecules in and out of the cells. In the kidney collecting duct, arginine vasopressin-dependent trafficking of aquaporin-2 (AQP2) fine-tunes reabsorption of water from pre-urine, allowing precise regulat...

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Detalles Bibliográficos
Autores principales: Hagströmer, Carl Johan, Hyld Steffen, Jonas, Kreida, Stefan, Al-Jubair, Tamim, Frick, Anna, Gourdon, Pontus, Törnroth-Horsefield, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482962/
https://www.ncbi.nlm.nih.gov/pubmed/37674034
http://dx.doi.org/10.1038/s41598-023-41616-1