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Regulation of brain endothelial cell physiology by the TAM receptor tyrosine kinase Mer

The receptor tyrosine kinase Mer (gene name Mertk) acts in vascular endothelial cells (ECs) to tighten the blood-brain barrier (BBB) subsequent to viral infection, but how this is achieved is poorly understood. We find that Mer controls the expression and activity of a large cohort of BBB regulators...

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Detalles Bibliográficos
Autores principales: Happonen, Kaisa E., Burrola, Patrick G., Lemke, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482977/
https://www.ncbi.nlm.nih.gov/pubmed/37673933
http://dx.doi.org/10.1038/s42003-023-05287-y