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Seizure enhances SUMOylation and zinc-finger transcriptional repression in neuronal nuclei

A single episode of pilocarpine-induced status epilepticus can trigger the development of spontaneous recurrent seizures in a rodent model for epilepsy. The initial seizure-induced events in neuronal nuclei that lead to long-term changes in gene expression and cellular responses likely contribute to...

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Detalles Bibliográficos
Autores principales: Soon, Hui Rong, Gaunt, Jessica Ruth, Bansal, Vibhavari Aysha, Lenherr, Clara, Sze, Siu Kwan, Ch’ng, Toh Hean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483055/
https://www.ncbi.nlm.nih.gov/pubmed/37694138
http://dx.doi.org/10.1016/j.isci.2023.107707