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Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis

Osteoarthritis (OA) is a prevalent degenerative disease of the elderly. The NRF2 antioxidant system plays a critical role in maintaining redox balance. Mitoquinone (MitoQ) is a mitochondria-targeted antioxidant. This research aimed to determine whether MitoQ alleviated OA and the role of the NRF2/Pa...

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Detalles Bibliográficos
Autores principales: Hou, Liangcai, Wang, Genchun, Zhang, Xiong, Lu, Fan, Xu, Jingting, Guo, Zhou, Lin, Jiamin, Zheng, Zehang, Liu, Haigang, Hou, Yanjun, Sun, Kai, Guo, Fengjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483061/
https://www.ncbi.nlm.nih.gov/pubmed/37694150
http://dx.doi.org/10.1016/j.isci.2023.107647