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Is Tranexamic Acid an Effective Prevention in the Formation of Epidural Fibrosis? Histological Evaluation in the Rats

OBJECTIVE: The present study aimed to determine the topical and systemic efficacy of tranexamic acid (TXA) on epidural fibrosis in a rat laminectomy model. METHODS: Thirty-two 12-month-old adult Sprague-Dawley rats were used in this study. Each rat underwent bilateral laminectomy at the L1 and L2 ve...

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Detalles Bibliográficos
Autores principales: Circi, Esra, Atici, Yunus, Baris, Alican, Senel, Ahmet, Leblebici, Cem, Tekin, Saltuk Bugra, Ozturkmen, Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurosurgical Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483163/
https://www.ncbi.nlm.nih.gov/pubmed/37334444
http://dx.doi.org/10.3340/jkns.2022.0249