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IL-18 and VEGF-A trigger type 2 innate lymphoid cell accumulation and pro-tumoral function in chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a hematologic malignancy associated to an unregulated growth of myeloid cells in bone marrow (BM) and peripheral blood (PB), characterized by the BCR-ABL1 translocation. Given the known cytokine impairment in the leukemic niche of CML, we investigated the impact of...

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Detalles Bibliográficos
Autores principales: Fiordi, Benedetta, Salvestrini, Valentina, Gugliotta, Gabriele, Castagnetti, Fausto, Curti, Antonio, Speiser, Daniel E., Marcenaro, Emanuela, Jandus, Camilla, Trabanelli, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483352/
https://www.ncbi.nlm.nih.gov/pubmed/37021528
http://dx.doi.org/10.3324/haematol.2022.282140