Stage-specific dual function: EZH2 regulates human erythropoiesis by eliciting histone and non-histone methylation

Enhancer of zeste homolog 2 (EZH2) is the lysine methyltransferase of polycomb repressive complex 2 (PRC2) that catalyzes H3K27 tri-methylation. Aberrant expression and loss-of-function mutations of EZH2 have been demonstrated to be tightly associated with the pathogenesis of various myeloid maligna...

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Detalles Bibliográficos
Autores principales: Li, Mengjia, Liu, Donghao, Xue, Fumin, Zhang, Hengchao, Yang, Qianqian, Sun, Lei, Qu, Xiaoli, Wu, Xiuyun, Zhao, Huizhi, Liu, Jing, Kang, Qiaozhen, Wang, Ting, An, Xiuli, Chen, Lixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Red Cell Biology & its Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483364/
https://www.ncbi.nlm.nih.gov/pubmed/37021526
http://dx.doi.org/10.3324/haematol.2022.282016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483364/
https://www.ncbi.nlm.nih.gov/pubmed/37021526
http://dx.doi.org/10.3324/haematol.2022.282016

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