Fabrication, optimization and characterization of an osmotic push-pull drug delivery system for paliperidone

OBJECTIVES: Paliperidone is a BCS class II drug with low solubility and high permeability. It has 28% absolute oral bioavailability and an elimination half-life of 23 h. An osmotic push–pull trilayer tablet currently available on the market has achieved controlled release of a low dose over an exten...

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Detalles Bibliográficos
Autores principales: Nangare, Sayali A., Ali, Asif H., Mahadik, Kakasaheb R., Patil, Sharvil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483505/
https://www.ncbi.nlm.nih.gov/pubmed/37693824
http://dx.doi.org/10.1016/j.jtumed.2023.08.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483505/
https://www.ncbi.nlm.nih.gov/pubmed/37693824
http://dx.doi.org/10.1016/j.jtumed.2023.08.002

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