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Effect of high-dose glucocorticoid treatment on human brown adipose tissue activity: a randomised, double-blinded, placebo-controlled cross-over trial in healthy men

BACKGROUND: Glucocorticoids (GCs) are widely applied anti-inflammatory drugs that are associated with adverse metabolic effects including insulin resistance and weight gain. Previous research indicates that GCs may negatively impact brown adipose tissue (BAT) activity in rodents and humans. METHODS:...

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Detalles Bibliográficos
Autores principales: Maushart, Claudia Irene, Sun, Wenfei, Othman, Alaa, Ghosh, Adhideb, Senn, Jaël Rut, Fischer, Jonas Gabriel William, Madoerin, Philipp, Loeliger, Rahel Catherina, Benz, Robyn Melanie, Takes, Martin, Zech, Christoph Johannes, Chirindel, Alin, Beuschlein, Felix, Reincke, Martin, Wild, Damian, Bieri, Oliver, Zamboni, Nicola, Wolfrum, Christian, Betz, Matthias Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483510/
https://www.ncbi.nlm.nih.gov/pubmed/37659283
http://dx.doi.org/10.1016/j.ebiom.2023.104771