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RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma

Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor in adults. The standard treatment achieves a median overall survival for GBM patients of only 15 months. Hence, novel therapies based on an increased understanding of the mechanistic underpinnings of GBM are desperate...

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Detalles Bibliográficos
Autores principales: Zhou, Jiesi, Kong, Yan Shu, Vincent, Krista M., Dieters‐Castator, Dylan, Bukhari, Amirali B., Glubrecht, Darryl, Liu, Rong‐Zong, Quilty, Douglas, Findlay, Scott D., Huang, Xiaowei, Xu, Zhihua, Yang, Rui Zhe, Zhang, Lanyue, Tang, Emily, Lajoie, Gilles, Eisenstat, David D., Gamper, Armin M., Fahlman, Richard, Godbout, Roseline, Postovit, Lynne‐Marie, Fu, YangXin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483612/
https://www.ncbi.nlm.nih.gov/pubmed/37057706
http://dx.doi.org/10.1002/1878-0261.13434