Asymmetric arginine dimethylation of cytosolic RNA and DNA sensors by PRMT3 attenuates antiviral innate immunity

The cytosolic RNA and DNA sensors initiate type I interferon signaling when binding to RNA or DNA. To effectively protect the host against virus infection and concomitantly avoid excessive interferonopathy at resting states, these sensors must be tightly regulated. However, the key molecular mechani...

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Detalles Bibliográficos
Autores principales: Zhu, Junji, Li, Xiong, Cai, Xiaolian, Zhou, Ziwen, Liao, Qian, Liu, Xing, Wang, Jing, Xiao, Wuhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483634/
https://www.ncbi.nlm.nih.gov/pubmed/37639603
http://dx.doi.org/10.1073/pnas.2214956120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483634/
https://www.ncbi.nlm.nih.gov/pubmed/37639603
http://dx.doi.org/10.1073/pnas.2214956120

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