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Machine Learning-Based Approach to Developing Potent EGFR Inhibitors for Breast Cancer—Design, Synthesis, and In Vitro Evaluation

[Image: see text] The epidermal growth factor receptor (EGFR) is vital for regulating cellular functions, including cell division, migration, survival, apoptosis, angiogenesis, and cancer. EGFR overexpression is an ideal target for anticancer drug development as it is absent from normal tissues, mar...

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Detalles Bibliográficos
Autores principales: Nada, Hossam, Gul, Anam Rana, Elkamhawy, Ahmed, Kim, Sungdo, Kim, Minkyoung, Choi, Yongseok, Park, Tae Jung, Lee, Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483653/
https://www.ncbi.nlm.nih.gov/pubmed/37692247
http://dx.doi.org/10.1021/acsomega.3c02799