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Triazolothiadiazoles and Triazolothiadiazines as New and Potent Urease Inhibitors: Insights from In Vitro Assay, Kinetics Data, and In Silico Assessment

[Image: see text] Hyperactivity of the urease enzyme induces the pathogenesis of peptic ulcers and gastritis. The identification of new urease inhibitors can reduce the activity of urease. Therefore, in the current study, we have evaluated 28 analogues of triazolothiadiazole and triazolothiadiazine...

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Detalles Bibliográficos
Autores principales: Uddin, Jalal, Ullah, Saeed, Halim, Sobia Ahsan, Waqas, Muhammad, Ibrar, Aliya, Khan, Imtiaz, Bin Muhsinah, Abdullatif, Khan, Ajmal, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483676/
https://www.ncbi.nlm.nih.gov/pubmed/37692208
http://dx.doi.org/10.1021/acsomega.3c03546