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Synthesis, characterization, and antiproliferative evaluation of novel sorafenib analogs for the treatment of hepatocellular carcinoma

Cancer is a disease triggered by an uncontrolled proliferation of a cluster of cells, typically originating from a single cell. Sorafenib, a widely utilized pharmaceutical, has limitations in clinical use due to pharmacokinetic challenges and the development of resistance mechanisms. This investigat...

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Detalles Bibliográficos
Autores principales: Jihad, Marwan Imad, Mahdi, Monther Faisal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483918/
https://www.ncbi.nlm.nih.gov/pubmed/37692003
http://dx.doi.org/10.4103/JAPTR.JAPTR_282_23