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Endothelial APC/PAR1 distinctly regulates cytokine-induced pro-inflammatory VCAM-1 expression

Introduction: Dysfunction of the endothelium impairs its’ protective role and promotes inflammation and progression of vascular diseases. Activated Protein C (APC) elicits endothelial cytoprotective responses including barrier stabilization, anti-inflammatory and anti-apoptotic responses through the...

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Detalles Bibliográficos
Autores principales: Birch, Cierra A., Wedegaertner, Helen, Orduña-Castillo, Lennis B., Gonzalez Ramirez, Monica L., Qin, Huaping, Trejo, JoAnn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483999/
https://www.ncbi.nlm.nih.gov/pubmed/37692066
http://dx.doi.org/10.3389/fmolb.2023.1211597