Ocular Pharmacology and Toxicology of TRPV1 Antagonist SAF312 (Libvatrep)

PURPOSE: To evaluate the pharmacology and toxicology of SAF312, a transient receptor potential vanilloid 1 (TRPV1) antagonist. METHODS: TRPV1 expression in human ocular tissues was evaluated with immunohistochemistry. Inhibition of calcium influx in Chinese hamster ovary (CHO) cells expressing human...

Descripción completa

Detalles Bibliográficos
Autores principales: Mogi, Muneto, Mendonza, Anisha E., Chastain, James, Demirs, John T., Medley, Quintus G., Zhang, Qin, Papillon, Julien P. N., Yang, Junzheng, Gao, Yan, Xu, YongYao, Stasi, Kalliopi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Cornea & External Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484039/
https://www.ncbi.nlm.nih.gov/pubmed/37672251
http://dx.doi.org/10.1167/tvst.12.9.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484039/
https://www.ncbi.nlm.nih.gov/pubmed/37672251
http://dx.doi.org/10.1167/tvst.12.9.5

Ejemplares similares