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Ocular Pharmacology and Toxicology of TRPV1 Antagonist SAF312 (Libvatrep)

PURPOSE: To evaluate the pharmacology and toxicology of SAF312, a transient receptor potential vanilloid 1 (TRPV1) antagonist. METHODS: TRPV1 expression in human ocular tissues was evaluated with immunohistochemistry. Inhibition of calcium influx in Chinese hamster ovary (CHO) cells expressing human...

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Detalles Bibliográficos
Autores principales:	Mogi, Muneto, Mendonza, Anisha E., Chastain, James, Demirs, John T., Medley, Quintus G., Zhang, Qin, Papillon, Julien P. N., Yang, Junzheng, Gao, Yan, Xu, YongYao, Stasi, Kalliopi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Cornea & External Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484039/ https://www.ncbi.nlm.nih.gov/pubmed/37672251 http://dx.doi.org/10.1167/tvst.12.9.5

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