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The Neuroprotective Effect of Activation of Sigma-1 Receptor on Neural Injury by Optic Nerve Crush

PURPOSE: This study aimed to explore the neuroprotective effects of sigma-1 receptor (S1R) on optic nerve crush (ONC) mice by upregulating its expression through intravitreal injection of adeno-associated virus (AAV). METHODS: The animals were divided into four groups. Mice that underwent ONC were a...

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Detalles Bibliográficos
Autores principales: Chen, Yao, Yang, Xueli, Mao, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484044/
https://www.ncbi.nlm.nih.gov/pubmed/37669061
http://dx.doi.org/10.1167/iovs.64.12.9