Simultaneous detection of DNA variation and methylation at HLA class II locus and immune gene promoters using targeted SureSelect Methyl-Sequencing

The Human Leukocyte Antigen (HLA) locus associates with a variety of complex diseases, particularly autoimmune and inflammatory conditions. The HLA-DR15 haplotype, for example, confers the major risk for developing Multiple Sclerosis in Caucasians, pinpointing an important role in the etiology of th...

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Detalles Bibliográficos
Autores principales: Kalomoiri, Maria, Prakash, Chandana Rao, Lagström, Sonja, Hauschulz, Kai, Ewing, Ewoud, Shchetynsky, Klementy, Kular, Lara, Needhamsen, Maria, Jagodic, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484099/
https://www.ncbi.nlm.nih.gov/pubmed/37691926
http://dx.doi.org/10.3389/fimmu.2023.1251772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484099/
https://www.ncbi.nlm.nih.gov/pubmed/37691926
http://dx.doi.org/10.3389/fimmu.2023.1251772

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