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Multi-ancestry genome-wide association study of 4069 children with glioma identifies 9p21.3 risk locus

BACKGROUND: Although recent sequencing studies have revealed that 10% of childhood gliomas are caused by rare germline mutations, the role of common variants is undetermined and no genome-wide significant risk loci for pediatric central nervous system tumors have been identified to date. METHODS: Me...

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Detalles Bibliográficos
Autores principales: Foss-Skiftesvik, Jon, Li, Shaobo, Rosenbaum, Adam, Hagen, Christian Munch, Stoltze, Ulrik Kristoffer, Ljungqvist, Sally, Hjalmars, Ulf, Schmiegelow, Kjeld, Morimoto, Libby, de Smith, Adam J, Mathiasen, René, Metayer, Catherine, Hougaard, David, Melin, Beatrice, Walsh, Kyle M, Bybjerg-Grauholm, Jonas, Dahlin, Anna M, Wiemels, Joseph L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484172/
https://www.ncbi.nlm.nih.gov/pubmed/36810956
http://dx.doi.org/10.1093/neuonc/noad042