Cargando…
Multi-ancestry genome-wide association study of 4069 children with glioma identifies 9p21.3 risk locus
BACKGROUND: Although recent sequencing studies have revealed that 10% of childhood gliomas are caused by rare germline mutations, the role of common variants is undetermined and no genome-wide significant risk loci for pediatric central nervous system tumors have been identified to date. METHODS: Me...
Autores principales: | Foss-Skiftesvik, Jon, Li, Shaobo, Rosenbaum, Adam, Hagen, Christian Munch, Stoltze, Ulrik Kristoffer, Ljungqvist, Sally, Hjalmars, Ulf, Schmiegelow, Kjeld, Morimoto, Libby, de Smith, Adam J, Mathiasen, René, Metayer, Catherine, Hougaard, David, Melin, Beatrice, Walsh, Kyle M, Bybjerg-Grauholm, Jonas, Dahlin, Anna M, Wiemels, Joseph L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484172/ https://www.ncbi.nlm.nih.gov/pubmed/36810956 http://dx.doi.org/10.1093/neuonc/noad042 |
Ejemplares similares
-
Molecular reclassification reveals low prevalence of germline predisposition in children with ependymoma
por: Foss-Skiftesvik, Jon, et al.
Publicado: (2023) -
Combinatorial batching of DNA for ultralow-cost detection of pathogenic variants
por: Stoltze, Ulrik Kristoffer, et al.
Publicado: (2023) -
9p21.3 Microdeletion involving CDKN2A/2B in a young patient with multiple primary cancers and review of the literature
por: Jensen, Marlene Richter, et al.
Publicado: (2022) -
An assessment on the incremental value of high-resolution magnetic resonance imaging to identify culprit plaques in atherosclerotic disease of the middle cerebral artery
por: Teng, Zhongzhao, et al.
Publicado: (2015) -
Redefining germline predisposition in children with molecularly characterized ependymoma: a population-based 20-year cohort
por: Foss-Skiftesvik, Jon, et al.
Publicado: (2022)