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Random allelic expression in the adult human body

Genes are typically assumed to express both parental alleles similarly, yet cell lines show random allelic expression (RAE) for many autosomal genes that could shape genetic effects. Thus, understanding RAE in human tissues could improve our understanding of phenotypic variation. Here, we develop a...

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Detalles Bibliográficos
Autores principales: Kravitz, Stephanie N., Ferris, Elliott, Love, Michael I., Thomas, Alun, Quinlan, Aaron R., Gregg, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484211/
https://www.ncbi.nlm.nih.gov/pubmed/36640362
http://dx.doi.org/10.1016/j.celrep.2022.111945