Cargando…

Germline-encoded specificities and the predictability of the B cell response

Antibodies result from the competition of B cell lineages evolving under selection for improved antigen recognition, a process known as affinity maturation. High-affinity antibodies to pathogens such as HIV, influenza, and SARS-CoV-2 are frequently reported to arise from B cells whose receptors, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vieira, Marcos C., Palm, Anna-Karin E., Stamper, Christopher T., Tepora, Micah E., Nguyen, Khoa D., Pham, Tho D., Boyd, Scott D., Wilson, Patrick C., Cobey, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484431/ https://www.ncbi.nlm.nih.gov/pubmed/37624867 http://dx.doi.org/10.1371/journal.ppat.1011603

Ejemplares similares

Measures of population immunity can predict the dominant clade of influenza A (H3N2) and reveal age-associated differences in susceptibility and specificity
por: Kim, Kangchon, et al.
Publicado: (2023)

Human Germline Antibody Gene Segments Encode Polyspecific Antibodies
por: Willis, Jordan R., et al.
Publicado: (2013)

Selection and Neutral Mutations Drive Pervasive Mutability Losses in Long-Lived Anti-HIV B-Cell Lineages
por: Vieira, Marcos C, et al.
Publicado: (2018)

Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire
por: Yeung, Yik Andy, et al.
Publicado: (2016)

Few Nuclear-Encoded Mitochondrial Gene Duplicates Contribute to Male Germline-Specific Functions in Humans
por: Eslamieh, Mohammadmehdi, et al.
Publicado: (2017)

Germline-encoded amino acids in the αβ T cell receptor control thymic selection
por: Scott-Browne, James P., et al.
Publicado: (2009)

Ancestry-specific predisposing germline variants in cancer
por: Oak, Ninad, et al.
Publicado: (2020)

Rational immunogen design to target specific germline B cell receptors
por: Jardine, J, et al.
Publicado: (2012)

An improved germline genome assembly for the sea lamprey Petromyzon marinus illuminates the evolution of germline-specific chromosomes
por: Timoshevskaya, Nataliya, et al.
Publicado: (2023)

Substituent Effects on the N–H Bond Dissociation Enthalpies, Ionization Energies, Acidities, and Radical Scavenging Behavior of 3,7-Disubstituted Phenoxazines and 3,7-Disubstituted Phenothiazines
por: Thao, Pham Thi Thu, et al.
Publicado: (2020)

Characterization of germline development and identification of genes associated with germline specification in pineapple
por: Zhao, Lihua, et al.
Publicado: (2021)

Cell-type-specific alternative splicing in the Arabidopsis germline
por: Misra, Chandra Shekhar, et al.
Publicado: (2022)

Functional properties of an ensemble of candidate germline-encoded precursors of the anti-MPER antibody 4E10
por: Finton, K, et al.
Publicado: (2012)

Germline-encoded amino acid-binding motifs drive immunodominant public antibody responses
por: Shrock, Ellen L., et al.
Publicado: (2023)

Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses
por: Guthmiller, Jenna J., et al.
Publicado: (2020)

Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans
por: Wu, Nelson R., et al.
Publicado: (2019)

Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila
por: Zamparini, Andrea L., et al.
Publicado: (2011)

Sequential enhancer state remodelling defines human germline competence and specification
por: Tang, Walfred W.C., et al.
Publicado: (2022)

Lineage-specific protection and immune imprinting shape the age distributions of influenza B cases
por: Vieira, Marcos C., et al.
Publicado: (2021)

Non-Cardiogenic Pulmonary Oedema Following the use of Gadolinium-Based Contrast Medium: A Case Report
por: Nguyen, Chilan, et al.
Publicado: (2020)

The structural basis of germline-encoded VH3 immunoglobulin binding to staphylococcal protein A
Publicado: (1993)

Amino acids at the site of V kappa-J kappa recombination not encoded by germline sequences
Publicado: (1987)

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory
por: Kaji, Tomohiro, et al.
Publicado: (2012)

Antibody homotypic interactions are encoded by germline light chain complementarity determining region 2
por: Leonard, Brandon, et al.
Publicado: (2022)

The context-specific role of germline pathogenicity in tumorigenesis
por: Srinivasan, Preethi, et al.
Publicado: (2021)

Radio resource allocation over fading channels under statistical delay constraints
por: Le-Ngoc, Tho, et al.
Publicado: (2017)

Germline BRCA2 mutations in men with breast cancer.
por: Mavraki, E., et al.
Publicado: (1997)

An Egg-Derived Sulfated N-Acetyllactosamine Glycan Is an Antigenic Decoy of Influenza Virus Vaccines
por: Guthmiller, Jenna J., et al.
Publicado: (2021)

Germline sex determination regulates sex-specific signaling between germline stem cells and their niche
por: Bhaskar, Pradeep Kumar, et al.
Publicado: (2022)

Congruency Encoding Effects on Recognition Memory: A Stage-Specific Account of Desirable Difficulty
por: Ptok, Melissa J., et al.
Publicado: (2019)

Germline competent mesoderm: the substrate for vertebrate germline and somatic stem cells?
por: Savage, Aaron M., et al.
Publicado: (2021)

Origin and segregation of the human germline
por: Castillo-Venzor, Aracely, et al.
Publicado: (2023)

Germline specification from pluripotent stem cells
por: Yao, Chunmeng, et al.
Publicado: (2022)

The male germline of angiosperms: repertoire of an inconspicuous but important cell lineage
por: Russell, Scott D., et al.
Publicado: (2015)

Common germline polymorphisms associated with breast cancer-specific survival
por: Pirie, Ailith, et al.
Publicado: (2015)

rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline
por: Jain, Devanshi, et al.
Publicado: (2017)

A Germline‐Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells
por: Zhang, Ru, et al.
Publicado: (2022)

Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6
por: Mohar, Isaac, et al.
Publicado: (2014)

Germline BRCA1 mutations increase prostate cancer risk
por: Leongamornlert, D, et al.
Publicado: (2012)

Assessment of Canine Pancreas‐Specific Lipase and Outcomes in Dogs with Hemodialysis‐Dependent Acute Kidney Injury
por: Takada, K., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_id8u6i8p9qahla502q514s9smq