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Exploring rigid-backbone protein docking in biologics discovery: a test using the DARPin scaffold
Accurate protein-protein docking remains challenging, especially for artificial biologics not coevolved naturally against their protein targets, like antibodies and other engineered scaffolds. We previously developed ProPOSE, an exhaustive docker with full atomistic details, which delivers cutting-e...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484509/ https://www.ncbi.nlm.nih.gov/pubmed/37692063 http://dx.doi.org/10.3389/fmolb.2023.1253689 |