Lomerizine attenuates LPS-induced acute lung injury by inhibiting the macrophage activation through reducing Ca(2+) influx

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening lung diseases with high mortality rates, predominantly attributable to acute and severe pulmonary inflammation. Lomerizine (LMZ) is a calcium channel blocker previously used in preventing and treating migrain...

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Detalles Bibliográficos
Autores principales: Song, Yunduan, Gou, Yusen, Gao, Jiameng, Chen, Dongxin, Zhang, Haibo, Zhao, Wenjuan, Qian, Feng, Xu, Ajing, Shen, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484514/
https://www.ncbi.nlm.nih.gov/pubmed/37693893
http://dx.doi.org/10.3389/fphar.2023.1236469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484514/
https://www.ncbi.nlm.nih.gov/pubmed/37693893
http://dx.doi.org/10.3389/fphar.2023.1236469

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