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Lomerizine attenuates LPS-induced acute lung injury by inhibiting the macrophage activation through reducing Ca(2+) influx
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening lung diseases with high mortality rates, predominantly attributable to acute and severe pulmonary inflammation. Lomerizine (LMZ) is a calcium channel blocker previously used in preventing and treating migrain...
Autores principales: | Song, Yunduan, Gou, Yusen, Gao, Jiameng, Chen, Dongxin, Zhang, Haibo, Zhao, Wenjuan, Qian, Feng, Xu, Ajing, Shen, Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484514/ https://www.ncbi.nlm.nih.gov/pubmed/37693893 http://dx.doi.org/10.3389/fphar.2023.1236469 |
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