Exosomes from osteoarthritic fibroblast-like synoviocytes promote cartilage ferroptosis and damage via delivering microRNA-19b-3p to target SLC7A11 in osteoarthritis

OBJECTIVE: Our previous studies revealed that normal synovial exosomes promoted chondrogenesis, and microRNA (miR)-19b-3p independently related to osteoarthritis (OA) risk. Subsequently, this study intended to further explore the effect of OA fibroblast-like synoviocyte (OA-FLS) exosomal miR-19b-3p...

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Detalles Bibliográficos
Autores principales: Kong, Ruina, Ji, Lianmei, Pang, Yafei, Zhao, Dongbao, Gao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484587/
https://www.ncbi.nlm.nih.gov/pubmed/37691947
http://dx.doi.org/10.3389/fimmu.2023.1181156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484587/
https://www.ncbi.nlm.nih.gov/pubmed/37691947
http://dx.doi.org/10.3389/fimmu.2023.1181156

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