Cargando…

Exosomes from osteoarthritic fibroblast-like synoviocytes promote cartilage ferroptosis and damage via delivering microRNA-19b-3p to target SLC7A11 in osteoarthritis

OBJECTIVE: Our previous studies revealed that normal synovial exosomes promoted chondrogenesis, and microRNA (miR)-19b-3p independently related to osteoarthritis (OA) risk. Subsequently, this study intended to further explore the effect of OA fibroblast-like synoviocyte (OA-FLS) exosomal miR-19b-3p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, Ruina, Ji, Lianmei, Pang, Yafei, Zhao, Dongbao, Gao, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484587/ https://www.ncbi.nlm.nih.gov/pubmed/37691947 http://dx.doi.org/10.3389/fimmu.2023.1181156

Ejemplares similares

MiRNA-126 expression inhibits IL-23R mediated TNF-α or IFN-γ production in fibroblast-like synoviocytes in a mice model of collagen-induced rheumatoid arthritis
por: Gao, Jie, et al.
Publicado: (2018)

Influence of Glucocorticoids on Cellular Senescence Hallmarks in Osteoarthritic Fibroblast-like Synoviocytes
por: Malaise, Olivier, et al.
Publicado: (2021)

Inflammation-Driven Secretion Potential Is Upregulated in Osteoarthritic Fibroblast-Like Synoviocytes
por: Chwastek, Jakub, et al.
Publicado: (2022)

Upregulating miR-181b promotes ferroptosis in osteoarthritic chondrocytes by inhibiting SLC7A11
por: Wang, Dexin, et al.
Publicado: (2023)

Interleukin-1 Induces the Release of Lubricating Phospholipids from Human Osteoarthritic Fibroblast-Like Synoviocytes
por: Thottakkattumana Parameswaran, Vishnu, et al.
Publicado: (2022)

Osteoarthritic Subchondral Bone Release Exosomes That Promote Cartilage Degeneration
por: Wu, Xiaoxin, et al.
Publicado: (2021)

The role of TNFRSF11B in development of osteoarthritic cartilage
por: Rodríguez Ruiz, Alejandro, et al.
Publicado: (2021)

Growth factors regulate phospholipid biosynthesis in human fibroblast-like synoviocytes obtained from osteoarthritic knees
por: Sluzalska, Katarzyna D., et al.
Publicado: (2017)

Identification of Novel Genes in Osteoarthritic Fibroblast-Like Synoviocytes Using Next-Generation Sequencing and Bioinformatics Approaches
por: Chen, Yi-Jen, et al.
Publicado: (2019)

Gas6/Axl Axis Activation Dampens the Inflammatory Response in Osteoarthritic Fibroblast-like Synoviocytes and Synovial Explants
por: Vago, Juliana P., et al.
Publicado: (2023)

Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling
por: Ding, Liang, et al.
Publicado: (2023)

The emerging role of fibroblast‐like synoviocytes‐mediated synovitis in osteoarthritis: An update
por: Han, Dafei, et al.
Publicado: (2020)

The Role of Autophagy in Osteoarthritic Cartilage
por: Kao, Wei-Chun, et al.
Publicado: (2022)

Control of Cell Migration and Inflammatory Mediators Production by CORM-2 in Osteoarthritic Synoviocytes
por: García-Arnandis, Isabel, et al.
Publicado: (2011)

Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage
por: Koike, Masato, et al.
Publicado: (2018)

The role of aggrecan in normal and osteoarthritic cartilage
por: Roughley, Peter J, et al.
Publicado: (2014)

Relationship between the pyroptosis of fibroblast-like synoviocytes and HMGB1 secretion in knee osteoarthritis
por: Xiao, Yancheng, et al.
Publicado: (2021)

N‐Glycan profiling of chondrocytes and fibroblast‐like synoviocytes: Towards functional glycomics in osteoarthritis
por: Fuehrer, Johannes, et al.
Publicado: (2021)

An osteoarthritis subtype characterized by synovial lipid metabolism disorder and fibroblast-like synoviocyte dysfunction
por: Cao, Xu, et al.
Publicado: (2022)

The Effect of Dexamethasone, Adrenergic and Cholinergic Receptor Agonists on Phospholipid Metabolism in Human Osteoarthritic Synoviocytes
por: Sluzalska, Katarzyna D., et al.
Publicado: (2019)

Cadherin-11 Provides Specific Cellular Adhesion between Fibroblast-like Synoviocytes
por: Valencia, Xavier, et al.
Publicado: (2004)

Lipid Transport and Metabolism in Healthy and Osteoarthritic Cartilage
por: Villalvilla, Amanda, et al.
Publicado: (2013)

Heparan sulfate functions are altered in the osteoarthritic cartilage
por: Shamdani, Sara, et al.
Publicado: (2020)

Up-regulation of P21-activated kinase 1 in osteoarthritis chondrocytes is responsible for osteoarthritic cartilage destruction
por: Ma, Wanli, et al.
Publicado: (2020)

Interphase fluorescence in situ hybridization analysis of fibroblast-like synoviocytes of patients with rheumatoid arthritis and osteoarthritis
por: Kiener, HP, et al.
Publicado: (2001)

Comparative Analysis of Peptide Composition and Bioactivity of Different Collagen Hydrolysate Batches on Human Osteoarthritic Synoviocytes
por: Simons, Viktor S., et al.
Publicado: (2018)

Differential Secretome Profiling of Human Osteoarthritic Synoviocytes Treated with Biotechnological Unsulfated and Marine Sulfated Chondroitins
por: Russo, Rosita, et al.
Publicado: (2020)

Building the synovium: cadherin-11 mediates fibroblast-like synoviocyte cell-to-cell adhesion
por: Kiener, Hans P, et al.
Publicado: (2005)

Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury
por: Lin, Feiyan, et al.
Publicado: (2022)

Synoviocytes protect cartilage from the effects of injury in vitro
por: Lee, Christina M, et al.
Publicado: (2013)

MRI-based hip cartilage measures in osteoarthritic and non-osteoarthritic individuals: a systematic review
por: Aguilar, Hector N, et al.
Publicado: (2017)

Autoimmune response in cartilage-delivered peptides in a patient with osteoarthritis
por: Nishioka, Kusuki
Publicado: (2004)

LKB1 Regulates Inflammation of Fibroblast-like Synoviocytes from Patients with Rheumatoid Arthritis via AMPK-Dependent SLC7A11-NOX4-ROS Signaling
por: Lee, Ha-Reum, et al.
Publicado: (2023)

Icariin Regulates Cellular Functions and Gene Expression of Osteoarthritis Patient-Derived Human Fibroblast-Like Synoviocytes
por: Pan, Lianhong, et al.
Publicado: (2017)

Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis
por: Li, Qingxian, et al.
Publicado: (2021)

Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes
por: Kato, Tomohiro, et al.
Publicado: (2014)

Cartilage repair in osteoarthritic patients: utopia or real opportunity?
por: Henrotin, Yves, et al.
Publicado: (2009)

Arthroscopic cartilage regeneration facilitating procedure for osteoarthritic knee
por: Lyu, Shaw-Ruey, et al.
Publicado: (2012)

Toll-like receptors in human chondrocytes and osteoarthritic cartilage
por: Sillat, Tarvo, et al.
Publicado: (2013)

Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage
por: Ali, Shabana Amanda, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_om71rrh5k5gl87m3k1i8v08lja