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The impact of gene polymorphism and hepatic insufficiency on voriconazole dose adjustment in invasive fungal infection individuals

Voriconazole (VRZ) is a broad-spectrum antifungal medication widely used to treat invasive fungal infections (IFI). The administration dosage and blood concentration of VRZ are influenced by various factors, posing challenges for standardization and individualization of dose adjustments. On the one...

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Detalles Bibliográficos
Autores principales: Li, Guolin, Li, Qinhui, Zhang, Changji, Yu, Qin, Li, Qi, Zhou, Xiaoshi, Yang, Rou, Yang, Xuerong, Liu, Hailin, Yang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484623/
https://www.ncbi.nlm.nih.gov/pubmed/37693307
http://dx.doi.org/10.3389/fgene.2023.1242711