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Insulin Inhibits Autophagy by Inhibiting the Binding of FoXO1 to the Promoter Region of GABARAPL1

Hyperinsulinemia and insulin resistance in T2D have a potent suppressive effect on hepatic autophagy, however, the underlying mechanisms remain unclear. To explore the effect of insulin on hepatic autophagy and its possible signaling pathways, HL-7702 cells were treated with insulin with or without...

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Detalles Bibliográficos
Autores principales: Hong, Tao, Wen, Jie, Mei, Lang, Li, Ruixiang, Zhou, Junlin, Li, Jiaoyang, Xiao, Xin-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484641/
https://www.ncbi.nlm.nih.gov/pubmed/37380030
http://dx.doi.org/10.1055/a-2119-3301