Mutation signature filtering enables high-fidelity RNA structure probing at all four nucleobases with DMS

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Chemical probing experiments have transformed RNA structure analysis, enabling high-throughput measurement of base-pairing in living cells. Dimethyl sulfate (DMS) is one of the most widely used structure probing reagents and has played a pivotal role in enabling next-generation single-molecule probi...

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Detalles Bibliográficos
Autores principales: Mitchell, David, Cotter, Jennifer, Saleem, Irfana, Mustoe, Anthony M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484685/
https://www.ncbi.nlm.nih.gov/pubmed/37334863
http://dx.doi.org/10.1093/nar/gkad522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484685/
https://www.ncbi.nlm.nih.gov/pubmed/37334863
http://dx.doi.org/10.1093/nar/gkad522

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