Archaeal Hel308 suppresses recombination through a catalytic switch that controls DNA annealing

Hel308 helicases promote genome stability in archaea and are conserved in metazoans, where they are known as HELQ. Their helicase mechanism is well characterised, but it is unclear how they specifically contribute to genome stability in archaea. We show here that a highly conserved motif of Hel308/H...

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Detalles Bibliográficos
Autores principales: Lever, Rebecca J, Simmons, Emily, Gamble-Milner, Rebecca, Buckley, Ryan J, Harrison, Catherine, Parkes, Ashley J, Mitchell, Laura, Gausden, Jacob A, Škulj, Sanja, Bertoša, Branimir, Bolt, Edward L, Allers, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484726/
https://www.ncbi.nlm.nih.gov/pubmed/37409572
http://dx.doi.org/10.1093/nar/gkad572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484726/
https://www.ncbi.nlm.nih.gov/pubmed/37409572
http://dx.doi.org/10.1093/nar/gkad572

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