Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide

Ligand/protein molecular recognition involves a dynamic process, whereby both partners require a degree of structural plasticity to regulate the binding/unbinding event. Here, we present the characterization of the interaction between a highly dynamic G-rich oligonucleotide, M08s-1, and its target p...

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Detalles Bibliográficos
Autores principales: Troisi, Romualdo, Napolitano, Valeria, Rossitto, Emanuele, Osman, Waleed, Nagano, Masanobu, Wakui, Koji, Popowicz, Grzegorz M, Yoshimoto, Keitaro, Sica, Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484730/
https://www.ncbi.nlm.nih.gov/pubmed/37503836
http://dx.doi.org/10.1093/nar/gkad634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484730/
https://www.ncbi.nlm.nih.gov/pubmed/37503836
http://dx.doi.org/10.1093/nar/gkad634

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