TLK1-mediated RAD54 phosphorylation spatio-temporally regulates Homologous Recombination Repair

Environmental agents like ionizing radiation (IR) and chemotherapeutic drugs can cause severe damage to the DNA, often in the form of double-strand breaks (DSBs). Remaining unrepaired, DSBs can lead to chromosomal rearrangements, and cell death. One major error-free pathway to repair DSBs is homolog...

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Detalles Bibliográficos
Autores principales: Ghosh, Ishita, Kwon, Youngho, Shabestari, Aida Badamchi, Chikhale, Rupesh, Chen, Jing, Wiese, Claudia, Sung, Patrick, De Benedetti, Arrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484734/
https://www.ncbi.nlm.nih.gov/pubmed/37439356
http://dx.doi.org/10.1093/nar/gkad589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484734/
https://www.ncbi.nlm.nih.gov/pubmed/37439356
http://dx.doi.org/10.1093/nar/gkad589

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