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Dynamic structure of T4 gene 32 protein filaments facilitates rapid noncooperative protein dissociation

Bacteriophage T4 gene 32 protein (gp32) is a model single-stranded DNA (ssDNA) binding protein, essential for DNA replication. gp32 forms cooperative filaments on ssDNA through interprotein interactions between its core and N-terminus. However, detailed understanding of gp32 filament structure and o...

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Detalles Bibliográficos
Autores principales: Cashen, Ben A, Morse, Michael, Rouzina, Ioulia, Karpel, Richard L, Williams, Mark C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484735/
https://www.ncbi.nlm.nih.gov/pubmed/37449435
http://dx.doi.org/10.1093/nar/gkad595