Human TRMT2A methylates tRNA and contributes to translation fidelity

5-Methyluridine (m(5)U) is one of the most abundant RNA modifications found in cytosolic tRNA. tRNA methyltransferase 2 homolog A (hTRMT2A) is the dedicated mammalian enzyme for m(5)U formation at tRNA position 54. However, its RNA binding specificity and functional role in the cell are not well und...

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Detalles Bibliográficos
Autores principales: Witzenberger, Monika, Burczyk, Sandra, Settele, David, Mayer, Wieland, Welp, Luisa M, Heiss, Matthias, Wagner, Mirko, Monecke, Thomas, Janowski, Robert, Carell, Thomas, Urlaub, Henning, Hauck, Stefanie M, Voigt, Aaron, Niessing, Dierk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484741/
https://www.ncbi.nlm.nih.gov/pubmed/37395448
http://dx.doi.org/10.1093/nar/gkad565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484741/
https://www.ncbi.nlm.nih.gov/pubmed/37395448
http://dx.doi.org/10.1093/nar/gkad565

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