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Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity
Modified parental histones are segregated symmetrically to daughter DNA strands during replication and can be inherited through mitosis. How this may sustain the epigenome and cell identity remains unknown. Here we show that transmission of histone-based information during DNA replication maintains...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484787/ https://www.ncbi.nlm.nih.gov/pubmed/37666988 http://dx.doi.org/10.1038/s41588-023-01476-x |