Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity

Modified parental histones are segregated symmetrically to daughter DNA strands during replication and can be inherited through mitosis. How this may sustain the epigenome and cell identity remains unknown. Here we show that transmission of histone-based information during DNA replication maintains...

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Detalles Bibliográficos
Autores principales: Wenger, Alice, Biran, Alva, Alcaraz, Nicolas, Redó-Riveiro, Alba, Sell, Annika Charlotte, Krautz, Robert, Flury, Valentin, Reverón-Gómez, Nazaret, Solis-Mezarino, Victor, Völker-Albert, Moritz, Imhof, Axel, Andersson, Robin, Brickman, Joshua M., Groth, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484787/
https://www.ncbi.nlm.nih.gov/pubmed/37666988
http://dx.doi.org/10.1038/s41588-023-01476-x

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