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Sigma-1 receptor expression in a subpopulation of lumbar spinal cord microglia in response to peripheral nerve injury

Sigma-1 Receptor has been shown to localize to sites of peripheral nerve injury and back pain. Radioligand probes have been developed to localize Sigma-1 Receptor and thus image pain source. However, in non-pain conditions, Sigma-1 Receptor expression has also been demonstrated in the central nervou...

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Detalles Bibliográficos
Autores principales: Schonfeld, Ethan, Johnstone, Thomas Michael, Haider, Ghani, Shah, Aaryan, Marianayagam, Neelan Joseph, Biswal, Sandip, Veeravagu, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484902/
https://www.ncbi.nlm.nih.gov/pubmed/37679500
http://dx.doi.org/10.1038/s41598-023-42063-8