PGC-1α inhibits M2 macrophage polarization and alleviates liver fibrosis following hepatic ischemia reperfusion injury

Oxidative stress can induce inflammation, promoting macrophage polarization and liver fibrosis following hepatic ischemia-reperfusion (I/R). Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) has anti-oxidant and anti-inflammatory activity. However, how PGC-1α regulates macrophage...

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Detalles Bibliográficos
Autores principales: Zhang, Yanting, Zhang, Linzhong, Zhao, Yanmian, He, Jing, Zhang, Yanghao, Zhang, Xiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484946/
https://www.ncbi.nlm.nih.gov/pubmed/37679346
http://dx.doi.org/10.1038/s41420-023-01636-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484946/
https://www.ncbi.nlm.nih.gov/pubmed/37679346
http://dx.doi.org/10.1038/s41420-023-01636-2

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